成人非惊厥性癫持续状态的临床及脑电图特点

Clinical and electroencephalogram features of nonconvulsive status epilepticus in adults

目的探讨成人非惊厥性癫持续状态(NCSE)的临床及脑电图特点。方法对7例NCSE患者的临床资料进行回顾性分析。结果本组7例NCSE患者中,复杂部分性NCSE 6例,全面性NCSE 1例。临床表现以不同程度意识障碍为主,伴反应迟钝、定向力障碍、自动症、精神行为异常等。脑电图检查均可见性发放,且癫波形态与临床表现有关。按癫持续状态治疗原则治疗后均明显好转。结论 NCSE患者临床表现复杂多样;脑电图改变明显且与临床症状可能有某些相关性,有助于诊断;及时治疗预后良好。

Objective To explore the clinical and electroencephalogram features of nonconvulsive status epilepticus（NCSE） in adults.Methods The clinical data of 7 NCSE patients were retrospective analyzed.Results Complex partial status epilepticus（CPSE） was identified in 6 patients and generalized nonconvulsive status epilepticus was seen in 1 case.The significant clinical presentations were disturbance of consciousness at different levels accompanied with or without clumsy,disorientation,automatism,mental and behavior disorder.Epileptic discharges were seen on electroencephalogram examinations in all patients,and the waveform of epileptic waves had relationship with clinical manifestation.Fine prognosis was induced after treatment according to therapeutic principle of status epilepticus.Conclusions The clinical manifestations are complex in NCSE patients.The electroencephalogram changes are significant,and it probably has some relativity with clinical symptoms and is helpful for diagnosis.Treatment in time will induce fine prognosis.