摘要
系统性硬皮病(SSc)是一种以皮肤及各系统胶原纤维硬化为特征的结缔组织疾病,临床上以皮肤增厚和内脏组织进行性纤维化为特征,常表现为雷诺现象、肺动脉高压、肺组织纤维化及多器官受累。SSc的治疗以免疫抑制剂为基础。随着各相关学科的发展,新型免疫抑制剂、生物制剂和干细胞移植等相继用于治疗SSc,并取得了显著的疗效,且对SSc的治疗也有了更深入的认识。本文就近年来治疗方面的进展作一综述。
Systemic sclerosis （SSc） is an autoimmune connective tissue disease characterized by fibrosis of skin and internal organs, clinical manifestations include thickening of the skin, Raynaud＇s phenomenon, pulmonary artery hypertension （ PAH）, pulmonary fibrosis （PF） and involvement of other visceral organs. The treatment of systemic sclerosis is based on immunodepressant. Recently, with the development of related science, new immunodepressant, biological agent, and stem cell transplantation is used to treat systemic sclerosis, and gains significant effects. Latest study showed a deeply understanding about the therapeutic effect of systemic sclerosis. This paper reviews the advances in studies on SSc therapy.
出处
《中国皮肤性病学杂志》
CAS
北大核心
2011年第5期393-396,400,共5页
The Chinese Journal of Dermatovenereology
关键词
系统性硬皮病
治疗
Systemic Sclerosis
Treatment
