急性痘疮样糠疹合并结节性血管炎1例

A Case Report of Pityriasis Lichenoides Etvarioliformis Acuta And Nodular Vasculitis

患者女,26岁。全身丘疹3月,四肢结节伴疼痛10天。皮损为圆形丘疹,表面有鳞屑覆盖,周围绕以红晕,以四肢明显,部分丘疹中心萎缩凹陷;左前臂、双小腿伸侧散在红色皮下结节,有压痛感。组织病理示:①小腿丘疹:表皮内见基底细胞灶性液化变性,真皮浅层血管周围大量淋巴细胞、组织细胞浸润,可见血管外红细胞。②小腿结节:皮下脂肪组织内见一大血管破坏,周围脂肪小叶弥漫性炎细胞浸润。诊断:急性痘疮样糠疹合并结节性血管炎。

A 26-year-old female presented with body pimples for three months, limbs nodules with tenderness for ten clays. Lesions are round papules to clear limbs, and which surface with scales, and around to flush, some papules center atrophy depression; the red subcutaneous nodule on the left forearm and shank with tenderness. After histopathological examination, the pathologic slice of the papules on her shank shows fueal liquefaction degeneration of basal cell in the epidermis,a large number of lymphocytes and histocytes around the superficial dermal vessels, and some erythrocytes out of the vessel. The nodules of her shank pathological shoe shows the angiolysis in the subcutaneous adipose tissue and the surrounding fat lobules with diffuse infihration of inflammatory cells. Diagnosis： Pityriasis lichenoides etvarioliformis aeuta and nodular vasculitis.