T_1声门癌CO_2激光声带切除阴性标本分析

Analysis of negative cordectomy specimens using CO_2 laser for T_1 glottic cancer

目的:探讨内镜CO2激光声带切除治疗T1声门癌时阴性声带切除的发生率及原因。方法:回顾性分析海军总医院2000-01-2010-02内镜CO2激光治疗的57例T1声门型喉癌患者的临床资料和病理资料。采取术前钳取活检和术中冷冻切片病理学检查。结果:声带切除Ⅰ型5例、Ⅱ型4例、Ⅲ型41例、Ⅳ型3例和Ⅴa型4例。术后标本阴性6例。阴性声带切除发生率为10.5%。结论:CO2激光声带切除时,应在保证切缘安全情况下,尽可能减少声带组织的切除。

Objective：This study determined presence or absence of residual cancer in the surgical specimen and analyzed outcomes.Method：A retrospective study of 57 patients with glottic carcinoma（7 Tis,47 T1a,and 3 T1b） treated from January 2000 to February 2010.All histological slides from the 57 patients were re-examined under the light microscope by the pathologist and the surgeon.We performed multiple biopsies and intraoperative biopsy as a diagnostic procedure.Result：There were 5,4,41,3,and 4 types Ⅰ to Ⅴ cordectomies,respectively.6 negative cordectomies（10.5%） were reported.Conclusion：The endoscopic treatment of T1 glottic cancer should be as conservative as possible.This assures resection of all the malignant tissue and preserves the maximum amount of healthy tissue.