同时性食管癌伴发肺癌同期手术切除的临床观察

Clinical observation of 16 patients with synchronous esophageal cancer and lung cancer treated with simultaneous esophagus and lung resection

目的 对同时性食管癌伴发肺癌的发病特点、临床特性、同期手术切除治疗效果及预后进行探讨.方法 收集2003年1月至2009年7月期间中国医学科学院肿瘤医院收治的16例同时性食管癌伴发肺癌同期手术切除患者的临床资料行回顾性分析.结果 本组男12例、女4例,男女比例为3∶1.发病年龄在51～76岁间,中位年龄67岁.本组16个食管癌病灶手术切除率为100%（1例为姑息行切除）;16个原发肺癌病灶手术切除率为100%（其中肺部肿瘤行肺叶切除7例,行楔形切除9例）.中位生存期为32个月.结论 食管癌术前行CT检查可及时发现可能存在的原发性肺癌;食管癌伴肺癌患者同期手术风险及预后可以接受.

Objective To study the pathogenesis, clinical features, curative effect and prognosis of esophageal cancer associated with lung cancer. Methods We reviewed 16 cases of esophageal cancer associated with lung cancer managed at our hospital between January 2003 and July 2009 and analyzed their clinical data. Results There were 16 cases of esophageal cancer associated with lung cancer. There were 67 years old （range：51 -76）. The resection rate of esophageal cancers was 100%. There was 1 case of nonradical resection. And the resection rate of lung cancer was 100%. There were radical resection （n =7） and wedge resection（n= 9）. The 1-year overall survival rate was 87.5%. Conclusion Lung lesions of esophageal cancer patients may be discovered by computed tomography screening of chest. More male patients than female patients are diagnosed with esophageal cancer associated with lung cancer. The operative risks and complication rates are generally acceptable.