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极性分子基团诱导的牙釉质原位仿生矿化研究 被引量:1

Biomimetic Mineralization of Tooth Enamel Induced by Functional Group in situ
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摘要 本研究采用原位仿生矿化的方法进行釉质龋的再生修复研究。以自然牙为标本,酸腐蚀形成缺损模型。酸蚀表面修饰极性分子基团-SO3-,在模拟体液和人工唾液中,进行仿生矿化实验;X-射线衍射和扫描电镜分析矿化形成晶体的形貌和组成。表面修饰极性基团有效地促进磷灰石在牙釉质缺损面的形成。基于高的钙磷离子浓度,在人工唾液中,长径比大的棒状六方羟基磷灰石晶体在牙釉质表面形成。研究结果表明在生理环境下有可能通过矿化实现再生修复。
出处 《中国生物医学工程学报》 CAS CSCD 北大核心 2011年第2期316-320,共5页 Chinese Journal of Biomedical Engineering
基金 国家自然科学基金重点项目(30870612)
关键词 仿生矿化 牙釉质 分子基团 biomimetic biomineralization enamel functional group induce
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