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骨形态发生蛋白的信号传导通路及其拮抗因子 被引量：5

Signal transduction and antagonists of bone morphogenetic proteins
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摘要 骨形态发生蛋白(BMPs)是一类属于转化生长因子-β超家族的多功能生长因子,具有诱导骨、软骨组织再生的能力。BMPs通过信号传导通路,引起靶基因的转录和表达。BMPs的生物学活性受多个水平的调控。本文着重就BMPs的信号传导通路及相关负性调控的研究进行综述。 Bone morphogenetic proteins（BMPs） are multifunctional cytokines belonging to the transforming growth factor-β（TGF-β）super-family.BMPs play key roles on the regeneration of bone and cartilage.BMPs regulate the transcription and expression of target genes by BMPs signaling pathway.A variety of processes modulate BMP activity.This review will focus on the BMPs signal pathway and related negative regulation.
作者 梁源 常新
机构地区 大连医科大学附属第二医院口腔科
出处 《大连医科大学学报》 CAS 2011年第2期187-191,共5页 Journal of Dalian Medical University
关键词 骨形态发生蛋白 信号传导通路 骨形态发生蛋白拮抗因子 BMPs signaling pathway BMP antagonist
分类号 R341 [医药卫生—基础医学]
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参考文献29

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二级参考文献28

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共引文献8

同被引文献104

引证文献5

二级引证文献20

大连医科大学学报
2011年 第2期

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