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p53在黑素细胞和黑素瘤代谢中的作用

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摘要 p53是重要的肿瘤抑制基因,本文结合p53蛋白的结构和功能,对于近年来有关p53在表皮黑素细胞和黑色素代谢中的作用,以及皮肤恶性黑素瘤(cutaneous malignant melanoma,CMM)中p53和p53通路相关蛋白的改变对黑素瘤发生发展影响的研究现状进行综述。
机构地区 汕头大学医学院
出处 《癌变.畸变.突变》 CAS CSCD 2011年第2期155-157,共3页 Carcinogenesis,Teratogenesis & Mutagenesis
基金 中华医学会-欧莱雅研究项目(S2010070806)
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参考文献18

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