AMH联合B超检查诊断多囊卵巢综合征的临床意义分析

The Clinic significance of diagnosing polycystic ovary syndrome by AMH and B-ultrasonography

目的:分析多囊卵巢综合征(Polycystic ovary syndrome,PCOS)患者的临床特点、内分泌改变和超声特征,并探讨相应指标的诊断意义。方法:研究组收集符合鹿特丹(2006)诊断标准的PCOS患者50例,检测其女性激素包括E2、FSH、LH、PRL、T,此外尚检测其抗苗勒氏管激素(AMH)水平,并使用B超检查测定其卵泡数量。同期选取正常女性23例,作为对照组,亦对上述指标进行测定。比较两组间临床特点、内分泌水平及B超检查等的状况,同时分析AMH的诊断价值。结果:PCOS患者女性激素指标中的LH、LH/FSH和T均高于对照组(P<0.05),而FSH低于对照组(P<0.05),此外,AMH与卵泡数目高于对照组,差异均有统计学意义(P<0.05)。AMH、B超指征与T水平三者联合诊断PCOS特异性最高。结论:测定AMH水平在临床工作中可以协助PCOS的诊疗。

Objective：To study the endocrinologic changes and ultrasonography changes of Polycystic ovary syndrome（PCOS） and their relationship.Methods：50 cases of PCOS patients in Zhongshan city were enrolled in this study,and 23 normal female were taken as control group.E2,FSH,LH,PRL,T and AMH both of the two groups were tested,besides ultrasonography were given to count follicular number.Then differences and relationship between them were studied.Results：LH,FSH,T and AMH had significant difference between the two groups.And AMH had corelationship with FSH and follicular number.Conclusion：AMH and LH/FSH can be alternative parameters to diagnose PCOS.