375位医务人员接种甲流疫苗不良反应分析

Analysis of the Safety of 375 H1N1 Influenza Vaccine Inoculators

目的:了解医务人员接种甲型H1N1流感裂解疫苗的不良反应(ADR)发生情况。方法:观察该医院375名医务工作者接种甲型H1N1流感裂解疫苗后的ADR,统计分析ADR发生率、出现时间、持续时间、转归等。结果:375例甲型H1N1流感裂解疫苗接种者中发生ADR10例,发生率2.7%。均为一般ADR,所有的ADR经对症治疗后均可治愈。结论:甲型H1N1流感裂解疫苗总体ADR以轻度ADR为主,均可治愈,疫苗的安全性较好。

Objective：To probe into the incidence rate of ADR and safety of H1N1 influenza A vaccine. Method ：375 medical workers inoculated with influenza A （H1N1 ） vaccines were included in this study. The incidence, occurrence time, duration and outcome of their adverse reactions were observed. Result：The total incidence of adverse reactions in 375 vaccinated people was 2.7% （ 10 of 375 ）. All the adverse reactions were able to heal spontaneously or were cured. Conclusion：H1N1 influenza A vaccine caused mild adverse drug reactions in a few subjects, and the symptoms could be quickly recovered spontaneously. The vaccine is relatively safe.