高频超声检测2型糖尿病颈总动脉内中膜与体质量指数的关系

The relationship between BMI and carotid artery IMT in type 2 diabetes mellitus

目的：探讨2型糖尿病（T2DM）体质量指数（BMI）与颈总动脉内中膜（IMT）及发生斑块的关系。方法：对90例35~79岁T2DM病人测量身高、体质量并计算BMI,按BMI值将研究对象分为正常体质量组、超质量组及肥胖组,对3组颈动脉进行检测,分析3组间BMI与颈总动脉IMT及斑块数量的关系。结果：T2DM病人IMT厚度随BMI增加而增加,两者呈中度正相关（r=0.49,P〈0.05）。正常体质量组、超质量组及肥胖组3组间IMT及斑块数量有显著性差异,以肥胖组最高（P〈0.05）;颈总动脉IMT厚度及斑块数量随BMI增加而增加;3组间有显著性差异,肥胖组最高（P〈0.05）。结论：T2DM病人BMI与IMT呈中度正相关,随BMI的增加,颈动脉粥样硬化及斑块的发生增加,BMI是T2DM患者发生动脉粥样硬化的独立危险因素。

Objective： To study the relationship between BMI and carotid artery intima-media thickness（IMT） in type 2 diabetes mellitus（T2DM）.Methods： BMI of 90 T2DM patients aged from 35 to 79 was calculated,the carotid artery was also detected by 2-dimensional and color doppler ultrasound.According to BMI,they were divided into three group： normals,overweigh and obesity.Results： Relationship between BMI and IMT was positive correlative.IMT was significantly different within the three groups（P0.05）.Compared with the BMI normal group,overweight and obesity＇s IMT had significant difference（P0.05） and it was highest in obesity＇s.The incidence of carotid artery atherosclerotic plaque was also higher（P0.05） .The highest was also in the obesity＇s group.Conclusion： The IMT of carotid artery has positive correlative to BMI in patient with T2DM.The incidence of carotid artery atherosclerotic plaque is higher in the overweight and obesity groups.