国产封堵器治疗先天性心脏病疗效的回顾性分析

Early and medium-term follow-up results of transcatheter closure of congenital cardiovascular diseases using domestic occluders

目的探讨我院心脏中心应用国产封堵器治疗先天性心脏病(congenital heart disease,CHD)846例有效性及安全性。方法 CHD患者,分别包括膜周部室间隔缺损、房间隔缺损和动脉导管未闭,经超声心动图检查局部解剖结构满足封堵条件。在局麻或全麻下对膜周部室间隔缺损、房间隔缺损和动脉导管未闭患者行经导管国产封堵器介入治疗,手术中经胸超声心动图和X线监测,术后3、6、12、24个月随访评价疗效。结果手术成功率98.7%(835/846)。术后即刻并发症5.8%(49/846),随访24个月迟发并发症3.4%(16/471)。结论 用国产封堵器介入治疗CHD操作简单、安全、损伤小、成功率高。

Objective To evaluate the effectiveness and safety of transcatheter closure of congenital heart diseases （CHD） using homemade occluders. Methods Patients diagnosed as having CHD were recommended for further transthoracic echoardiographic assessment using multiple standard views. All the procedures were performed under local or general anesthesia. Transthoracic echocardiography and X rays were used to monitor the procedure. Effectiveness was evaluated at 3, 6, 12 and 24 months after the procedure. Results The success rate of device implantation was 98.7%. The rate of immediate post - procedure complication was 5.8% （49/ 846） and the rate of delayed complications after 24 - month follow - up was 3.4% （ 16/471 ）. Conclusions The treatment of CHD with domestic occluders is a simple, safe, reliable and efficient method with a high success rate and high effectiveness.