脊椎骨转移瘤合并压缩性骨折的综合治疗

Comprehensive treatment of metastatic spinal cancer accompanying compression fracture

目的探讨脊椎骨转移瘤合并压缩性骨折的综合治疗方法。方法分析我院脊椎骨转移瘤合并压缩性骨折的癌症患者73例,A组40例行含手术的综合治疗,B组33例行不含手术的综合治疗。结果随诊6个月,A组40例中35例生活基本自理,生活质量状况评定标准(KPS评分)在70分以上,4例因肿瘤转移和播散死亡。B组33例中20例有效,KPS评分在70分以上;11例KPS评分≤60分;2例死亡,死亡前均出现截瘫。结论脊椎骨转移瘤合并压缩性骨折患者在综合治疗基础上,适时选择外科手术治疗可提高生活质量。

Objective To study the comprehensive treatment of metastatic spinal cancer accompanying compression fracture.Methods Seventy-three patients with metastatic spinal cancer accompanying compression fracture admitted to our hospital were divided into group A（n=40） and group B（n=33）.Patients in group A received comprehensive therapy plus operation,and those in group B underwent comprehensive therapy without operation.Results The patients were followed up for 6 months.Of the 40 patients in group A,35 could take care of themselves with a KPS over 70,4 died of cancer metastasis and spreading during the follow-up period.Of the 33 patients in group B,20 had a satisfactory outcome with a KPS over 70,11 could not take care of themselves with a KPS≤60,and 2 became paraplegic before they died during the follow-up period.Conclusion The quality of life of patients with metastatic spinal cancer accompanying compression fracture can be improved after comprehensive treatment plus operation at an appropriate time.