不同匀浆膳制剂对老年糖尿病管饲患者生化水平及血红蛋白的影响

Effect of different homogenated diets on blood biochemistry and hemoglobin in elderly type 2 diabetic patients with tube feeding

目的观察不同匀浆膳制剂对老年糖尿病管饲患者生化水平及血红蛋白的影响。方法 56例2型老年糖尿病管饲患者,按照匀浆膳种类分为自制匀浆膳组、三九匀浆膳组和肠内营养乳剂(TPF-D)组,收集患者人体测量指标(身高、体重、腰围、臀围)、生化检测结果及血红蛋白(检验指标均累计>4次,取平均值)。结果三组患者血清尿酸、铁、钙及血红蛋白均较管饲前明显增高(P<0.05),自制匀浆膳组较管饲前血钠升高、血钾降低(P<0.05);管饲期间:肠内营养乳剂(TPF-D)组与其他两组比较血清尿酸较高(P<0.05);三九匀浆膳组与其他两组比较载脂蛋白A1较高(P<0.05);自制匀浆膳组与其他两组比较血钠增高、血钾降低(P<0.05);其余指标组间无显著性差异。结论三种匀浆膳均可保证老年糖尿病管饲患者的营养需要,因其各有特点和不足,长期应用应根据患者不同情况合理搭配肠内营养制剂。

Objective To observe the effect of different homogenated diets on blood biochemistry and hemoglobin in elderly type 2 diabetic patients with tube feeding.Methods Fifty-six type 2 diabetic patients were divided into home-made homogenated diet group,Sanjiu homogenated diet group and TPF-D group.Parameters of body height,body weight,waist circumference and hip circumference,as well as findings of biochemical testing including hemoglobin（Hb） of the patients were analyzed.Results The serum levels of uric acid（sUA）,iron（Fe）,calcium（Ca） and Hb were significantly higher in those after feeding the diets than in those before feeding the diets（P〈0.05）.The blood sodium（Na） level was higher while the blood potassium（K） level was lower in home-made homogenated diet group than in the other two groups（P〈0.05）.The sUA level was significantly higher in TPF-D group than in the other groups（P〈0.05）.The ApoA1 level was significantly higher in Sanjiu homogenated diet group than in the other groups（P〈0.05）.The blood Na level was higher and the blood K level was lower in home-made homogenated diet group than in the other groups（P〈0.05）.No significant difference was found in other parameters among the 3 groups.Conclusion The three homogenated diets can meet the nutrition requirements of elderly diabetic patients with tube feeding.Rational addition of nutrients according to the different conditions of such patients should be stressed if these diets are used for a long time due to their different advantages and disadvantages.