药动/药效相关性进展及其在中药研究中的应用

The progress of PK-PD model and the method of status analysis in Chinese traditional medicine

近年来,药动/药效(PK-PD)的联合模型在药物研究中越来越重要,除了一些传统的模型外,一些新的方法也被应用于药动/药效联合模型中,在数据统计方面也出现了一些新分析方法,如神经网络分析方法、规划求解与遗传算法相结合法等。本文综述了药动/药效的相关性以及数据分析方法的研究进展及其在中药研究中的展望。

PK-PD model plays a more and more important role in the medicine researches in these years.Besides classical models,new methods were applied into the PK-PD model,while there are new data analysis methods in the PK-PD.For example,neural network,programming solution combined with Genetic Algorithm,ect.This paper reviews the relationship of the PK-PD and the data analysis methods including its application in TCM as well.