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哺乳动物雷帕霉素靶蛋白在中枢神经系统再生中的作用

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摘要 成年哺乳动物中枢神经系统(central nervous system, CNS)损伤后再生困难的主要原因是抑制性微环境的存在和其内在的生长能力低下[1].目前关于损伤微环境的大量研究显示,单纯阻断环境抑制信号而不激活神经元内在生长状态(intrinsic growth state),其再生是有限的[2].
出处 《解剖学杂志》 CAS CSCD 北大核心 2011年第2期262-264,共3页 Chinese Journal of Anatomy
基金 重庆市自然科学基金(CSTC,2008BB5281)
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参考文献1

  • 1Zhigang He F.M. Kirby Neurobiology Center, Children’s Hospital, and Department of Neurology, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA..Intrinsic control of axon regeneration[J].The Journal of Biomedical Research,2010,24(1):2-5. 被引量:6

二级参考文献10

  • 1Cafferty WB,McGee AW,Strittmatter SM.Axonal growth therapeutics: regeneration or sprouting or plasticity?[].Trends in Neurosciences.2008
  • 2Blesch A,Tuszynski MH.Spinal cord injury: plasticity, regeneration and the challenge of translational drug development[].Trends in Neurosciences.2009
  • 3Goldberg JL,Barres BA.The relationship between neuronal survival and regeneration[].Annual Review of Neuroscience.2000
  • 4Goldberg J L,Klassen M P,Hua Y,et al.Amacrine-signaled loss of intrinsic axon growth ability by retinal ganglion cells[].Science.2002
  • 5Park KK,Liu K,Hu Y,et al.Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway[].Science.2008
  • 6Busch,SA,Silver,J.The role of extracellular matrix in CNS regeneration[].Current Opinion in Neurobiology.2007
  • 7Lauren C. Case and Marc Tessier-Lavigne.Regeneration of the adult central nervous system[].Current Biology.2005
  • 8Filbin MT.Recapitulate development to promote axonalregeneration:good or bad approach?[].Philos Trans RSoc Lond B Biol Sci.2006
  • 9GLENN Y,ZHIGANG H.Glial inhibition ofCNS axon regeneration[].Nature ReviewsNeuroscience.2006
  • 10Aguayo,AJ,Rasminsky,M,Bray,GM,Carbonetto,S,Mckerracher,L,Villegasperez,MP,Vidalsanz,M,Carter,DA.Degenerative and regenerative responses of injured neurons in the central nervous system of adult mammals[].Philosophical Transactions of the Royal Society of London.1991

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