经皮肺穿刺活检注射生理盐水与凝血酶预防常见并发症的对比

Comparison of preventing common complications in percutaneous needle biopsy of lung using normal saline or thrombin solutions injection

目的:对比使用生理盐水与凝血酶在经皮肺穿刺活检术中预防常见并发症的效果。方法:回顾性分析注射生理盐水和凝血酶在CT引导下经皮肺穿刺活检且年龄≥55岁的连续病例资料各50例,A组注射生理盐水,B组注射凝血酶。对比两组患者注射液体的分布情况和常见并发症的发生率。结果:100例均穿刺成功。A组患者液体沿穿刺针道分布较广、甚至呈斑片状;B组患者液体基本沿穿刺针道呈线状分布。A组发生气胸4例,肺出血8例;B组气胸3例,肺出血2例。结论:注射凝血酶在预防经皮肺穿刺活检常见并发症方面较注射生理盐水更有效。

Objective：To compare the effect of using normal saline（NS） or thrombin solution（TS） injection to prevent common complications in percutaneous needle biopsy of lung.Methods：100 patients with the age ≥55 years had percutaneous needle biopsy of lung.The patients were divided into two groups with 50 patients in each group,Group A with NS and Group B with TS injected via the puncture needle during the pereutaneous needle biopsy procedure.Results：Percutaneous needle biopsy of lung were successfully performed in all these 100 patients.The injected fluid distributed more extensively along the puncture pathway even showing patchy distribution in Group A,while in Group B linear distribution were showed along the puncture pathway.Pneumothorax（n=4） and intra-pulmonary hemorrhage（n=8） were occurred in Group A,while only 3 cases and 2 cases respectively in Group B.Conclusion：Thrombin solution injection was more effective than NS in the prevention of common complications in percutaneous needle biopsy of lung.