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高同型半胱氨酸血症与冠状动脉粥样硬化 被引量:4

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摘要 1932年,Du Vigneaud首次发现Hcy是一种含硫氨基酸,系蛋氨酸的中间代谢产物。1969年McCull提出高同型半胱氨酸血症(Hcy)与动脉粥样硬化(AS)发生有关的观点以来,国内外学者对此进行了大量研究,结果显示Hcy是AS及其血管并发症的独立危险因素。
作者 杨铁勇 李霞
出处 《中国社区医师(医学专业)》 2011年第14期6-7,共2页
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参考文献16

  • 1Welch GN,Loslalzo J.Homocysteine and atberothrombosis[J].N Engl J Med,1998,338(15):1042-1050.
  • 2Kang SS,Wrong PWK,Malinow MR.Hyperhomocysteinemia as a risk factor occlusive vascular disease[J].Ann Rev Nutr,1992,12:279-298.
  • 3James SJ,Beresford SAA,Motulsky AG,et al.Preventing coronary heart disease:B Vitamins and homocysteine[J].Am J Clin Nutr,1999,70(4):495-501.
  • 4Boddie AM,Steen MT,Sullivan KM,et al.Cystathionine betasynthase deficiency:detection of hetero zygotesby the ratios of homocysteine to cysteine and folate[J].Metab Clin Exp,1998,47(2):207.
  • 5Hoogeveen EK,Kostense PJ,Beks PJ,et al.Hyperhomocysteinemia is associated with an increased risk of cardiovascular disease,especially in noninsulindependent diabetes mellitus:a population study[J].Arterioscler Thromb Vasc Biol,1998,18:133-138.
  • 6Hucks D,Thuraisingham RC,Raftery MJ,et al.Homocysteine induced impairment of nitric oxide-dependent vasorelaxationis reversible by the superoxide dismutase mimetic Tempol[J].Nephrol Dial Transp lant,2004,19(8):1999-2005.
  • 7Lang D,Kredan MB,Moat SJ,et al.Homocysteine-induced inhibition of endothelium-dependent relaxation in rabbit aorta:role for superoxide anions[J].Arterioscler Thromb Vasc Biol,2000,20:422-427.
  • 8王玉芳,王树人,陈海艳,杨志梅,顾玲.同型半胱氨酸对培养内皮细胞损伤的研究[J].中国病理生理杂志,2001,17(3):268-270. 被引量:27
  • 9Morita H,Kurihara H,Yoshida S,et al.Dietinduced hyperhomocysteinemia exacerbates neoiintima forrmmaation in rat carotid arteries after balloon injury[J].Circulation,2001,103(1):133-139.
  • 10Durand P,Lussier-Xacan S,Blache D.Acute methionine loadinduced hyperhomocysteinemia enhances platelet aggregation,thromboxane biosynthesis,and macrophage-derived tissue factor activity in rats[J].Faseb J,1997,11:1157-1168.

二级参考文献14

  • 1张林华,刘秉文.一次性密度梯度超速离心分离人血清脂蛋白[J].生物化学与生物物理学报,1989,21(3):257-260. 被引量:116
  • 21,BostomAG,SelhubJ.Homocysteineandarteriosclerosis:subclinicalandclinicaldiseaseassociation.Circulation,1999,99:2361~2363.
  • 32,OmennGS,BeresfordSAA,MotulskyAG.Preventingcoronaryheartdisease:Bvitaminsandhomocysteine.Circulation,1998,97:421~424.
  • 43,Homocysteinelowingtrialists'collaboration.Lowingbloodhomocysteinewithfolicacidbasedsupplements:Meta-analysisofrandomizedtrials.BMJ,1998,316:894~898.
  • 54,UbbinkJB,VermaakWJH,vanderMerweA,etal.Vitaminrequirementsforthetreatmentofhyperhomocysteineminainhumans.JNutr,1994,124:1927~1933.
  • 65,DurandP,FortinLJ,LussierCS,etal.Hyperhomocysteinemiainducedbyfolicaciddeficiencyandmethionineload-applicationsofamodifedHPLCmethod.ClinicalChimicaActa,1996,252:83~93.
  • 76,VandenBergM,FrankenDG,BoersGHJ,etal.CombinedvitaminB6plusfolicacidtherapyinyoungpatienswitharteriosclerosisandhyperhomocysteinemia.JVascSurg,1994,20:933~940.
  • 87,SelhubJ,MillerJW.Thepathogenesisofhomocys-teinemia:interruptionofthecoordinateregulationbyS-adenosylmethionineoftheremethylationandtranssulfurationofhomocysteine.AmJClinNutr,1992,55:131~138.
  • 98,KoD,RobinsonK.Homocysteineandcardiovasculardisease.CVR&R,1998,19(8):49~61.
  • 109,BoersGHJ,SmalsAGH,TrijbelsFJM,etal.Heterozygosityforhomocysteineinprematureperipheralandcerebralocclusivearterialdisease.NEnglJMed,1985,313:709~715.

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