摘要
目的:观察地塞米松对预防PICC置管术后机械性静脉炎发生的效果。方法:将48例患者随机分成两组,每组24例。实验组置管时将5mg地塞米松注射液加入50ml生理盐水中,用该溶液完全浸泡PICC导管后再行插管。对照组置管时采用生理盐水浸泡PICC导管后再插管。观察两组患者PICC置入术后7天内静脉炎的发生情况。结果:实验组机械性静脉炎的发生率较对照组明显降低(P<0.05);其发生程度亦明显减轻(P<0.001)。结论:采用地塞米松稀释液浸泡导管可以有效预防PICC置管术后机械性静脉炎的发生。
Objective：To observe the effect of dexamethasone for preventing and treating mechanical phlebitis indued by PICC.Methods：Based on a full exposure of informed consent,48 patients given PICC were divided equally into two groups.The central catheter of experimental group was treated with dexamethasone（5mg DMX in 50ml 0.9% NaCl） before PICC.The control group was given usual management.The incidence of treating phlebitis,and the effect of dexamethasone was compared between two groups.Results：Compared with the control group,the incidence of phlebitis in experimental group was decreased significantly（P0.05）,and the seriousness of phlebitis reduced obviously（P0.001）.Conclusion：The data showed that treament with dexamethasone before PICC could prevent mechanical phlebitis caused by PICC catheterization.
关键词
经外周静脉中心静脉置管
地塞米松
机械性静脉炎
dexamethasone
peripherally inserted central catheter（PICC）
mechanical phlebitis
