彩色多普勒超声引导经皮经肝动脉分支穿刺栓塞化疗治疗原发性肝癌

Transcutaneous hepatic arterioles puncture and embolitic chemotherapy for hepatocellular carcinoma by the guidance of color Doppler ultrasonography

目的评价彩色多普勒超声（ＣＤＵ）引导经皮经肝动脉分支穿刺栓塞化疗（ＴＡＥ）治疗原发性肝癌（ＨＣＣ）的可行性和临床价值。方法对８例中、晚期ＨＣＣ行１２次ＣＤＵ引导下ＴＡＥ治疗。结果依靠ＣＤＵ技术准确识别肿瘤供血动脉，对≥２ｍｍ肝内动脉结构经皮细针穿刺成功率为１００％。术后ＣＴ扫描结果分析，证实栓塞剂准确进入病变区域。全组术后无严重并发症发生，平均生存期为７．５个月，最长１例存活１３个月，仍健在。结论彩色多普勒超声引导经皮经肝动脉分支穿刺栓塞化疗治疗ＨＣＣ是一种简便、安全和实用的新技术，值得深入研究和探讨。

Objective\ To evaluate the possibility and clinical value on transcutaneous hepatic arteriole puncture for embolitic chemotherapy (TAE) by the guidance of color Doppler ultrasonography (CDU).Methods\ Twelve punctures on 8 cases in middle or late stage of hepatocellular carcinoma (HCC) have been performed.Results\ THAP were all successful on those with arteriole lumen diameter ≥2 mm by recognization for tumor feeding arteries with CDU. Whereas drugs have exactly been injected into arterioles which were confirmed by CT scan. No any complication occured in whole group. Mean survival period was 7.5 months, and the longest one has been 13 months and the patient is still in life.Conclusions\ The HCC theraputic procedure with THAP TAE is a new, simple, safe and practical technique and should be study continuously.