期刊文献+

阿尔茨海默病与原发性开角型青光眼的关系 被引量:1

原文传递
导出
摘要 阿尔茨海默病(Alzheimer's disease,AD)作为一种神经系统的老年退行性疾病,近年来发病率有逐年上升的趋势.研究发现AD患者常伴有眼部异常,包括视力、色觉、对比敏感度、瞳孔大小、瞳孔运动、视觉电生理的改变等,同时伴有视网膜神经节细胞数量的减少以及神经纤维层厚度降低.AD患者出现各种眼部异常的比例明显增加.随着青光眼相关研究的深入,发现AD与原发性开角型青光眼在病理改变、发病机制上有很多相似之处.AD与原发性开角型青光眼是否相关需进一步研究证实.
出处 《国际眼科纵览》 2011年第2期82-86,共5页 International Review of Ophthalmology
  • 相关文献

参考文献34

  • 1Miller N,Drachman DA.The optic nerve:a window into diseases of the brain?.Neurology,2006,67:1742-1743.
  • 2Wostyn P,Audenaert K,De Deyn PP.Alzheimer's disease:cerebral glaucoma?.Med Hypotheses,2010,74:973-977.
  • 3Engelborghs S,De Vreese K,Van de Casteele T,et al.Diagnostic performance of a CSF-biornarker panel in autopsy-confirmed dementia.Neurobiol Aging,2008,29:1143-1159.
  • 4Yoneda S,Hara H,Hirata A,et al.Vitreous fluid levels of β-amyloid(1-42) and tau in patients with retinal diseases.Jpn J Ophthalmol,2005,49:106-108.
  • 5Gupta N,Fong J,Ang LC,et al.Retinal tau pathology in human glaucomas.Can J Ophthalmol,2008,43:53-60.
  • 6McKinnon SJ,Lehman DM,Kerrigan-Baumrind LA,et al.Caspase activation and amyloid precursor protein cleavage in rat ocular hypertension.Invest Ophthalmol Vis Sci,2002,43:1077-1087.
  • 7Bayer AU,Keller ON,Ferrari F,et al.Association of glaucoma with neurodegenerative diseases with apoptotic cell death:Alzheimer's disease and Parkinson's disease.Am J Ophthalmol,2002,133:135-137.
  • 8Tamura H,Kawakami H,Kanamoto T,et al.High frequency of open-angle glaucoma in Japanese patients with Alzheimer's disease.J Neurol Sci,2006,246:79-83.
  • 9Guo L,Salt TE,Luong V,et al.Targeting amyloid-beta in glaucoma treatment.Proc Natl Acad Sci U S A,2007,104:13444-13449.
  • 10Berdahl JP,Allingham RR,Johnson DH.Cerebrospinal fluid pressure is decreased in primary open-angle glaucoma.Ophthalmology,2008,115:763-768.

同被引文献18

  • 1Weinreb RN, Khaw PT. Primary open-angle glaucoma[J]. Lan- cet, 2004, 363(9422): 1711-1720.
  • 2Guo L, Salt TE, Luong V, et al. Targeting amyloid-beta in glau- coma treatment[J]. Proc Natl Acad Sci USA, 2007, 104(33): 13444-13449.
  • 3Petersen RC, Doody R, Kurz A, et al. Current concepts in mild cognitive impairment[J]. Arch Neurol, 2001, 58(12):1985-1992.
  • 4Wang N, Xie X, Yang J, et al. Orbital cerebrospinal fluid space in glaucoma: the Beijing intracranial and intraocular pressure (iCOP)study[J]. Ophthalmology, 2012, 119(10): 2065-2073.
  • 5Petersen RC, Smith GE, Waling SC, et al. Mild cognitive impair- ment: clinical characterization and outcome[J]. Arch Neurol, 1999, 56(3): 303-308.
  • 6Bayer AU, Ferrari F, Erb C. High occurrence rate of glaucoma among patients with Alzheimer' s disease[J]. Eur Neurol, 2002, 47(3): 165-168.
  • 7Hinton DR, Sadun AA, Blanks JC, et al. Optic-nerve degenera- tion in Alzheimer's disease[J]. N Engl J Med, 1986, 315(8): 485-487.
  • 8Bizrah M, Guo L, Cordeiro MF. Glaucoma and Alzheimer's dis- ease in the elderly[J]. Aging Health, 2011, 7(5): 719-733.
  • 9Sugiyama T, Utsunomiya K, Ota H, et al. Comparative study of cerebral blood flow in patients with normal-ten- sion glaucoma and control subjects[J]. Am J Ophthalmol, 2006, 141(2): 394-396.
  • 10Fernandez-Martlnez M, Castro J, Molano A, et al. Prevalence of neuropsychiatric symptoms in Alzheimer's disease and vascular dementia[J]. Curr Alzheimer Res, 2008, 5(1): 61-69.

引证文献1

二级引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部