复方苦参注射液在常用输液中的稳定性考察

Compatible Stability of Compound Sophora flavescentis Injection in Common Infusion

目的:考察复方苦参注射液与3种临床常用输液配伍的稳定性,为临床应用提供参考。方法:模拟临床用药情况,将复方苦参注射液与3种常用溶剂配伍,观察配伍前,后各个输液的pH和不溶性微粒的变化情况,以及6 h内的稳定性。结果:复方苦参注射液与0.9%的NaCl比5%葡萄糖和10%葡萄糖更宜配伍使用。结论:复方苦参注射液配伍在6 h内基本稳定。

Objective：To observe the stability of the compound of Sophora flavescentis injection and three kinds of clinical commonly used injections for compatibility to provide reference for clinical application.Method： Clinical pharmacy situation was simulated with compound Sophora flavescentis injection compatible with three kinds of common injections to observe the stability in 6 h and the changing situation of the pH and insoluble particles of every transfusion before and after compatibility.Result： The compound Sophroa flavescentis injection compatible with 0.9%NaCl was more appropriate than compatible with 5% glucose and 10% glucose.Conclusion： The compatibility of compound Sophora flavescentis injection is basically stable in 6 h.