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甘草苷提取工艺正交试验优化 被引量:9

Orthogonal Test for Optimization of Liquiritin Extraction Process
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摘要 目的:研究甘草苷最佳提取工艺条件。方法:采用正交试验优选的乙醇体积分数、用量、提取时间和提取次数对甘草苷提取率的影响;采用HPLC以甘草苷含量为考察指标。结果:甘草苷最佳提取条件为10倍量70%乙醇,回流提取2次,每次3 h。结论:本方法提取效率高,为工业化生产提供了实验依据。 Objective:To optimize the extracting technology of liquiritin in glycyrrhiza.Method: The amount of solvent,the extracting time and the extracting frequencies were assayed by orthogonal test with different concentrations of alcohol as the solvent to detect their influences on the extraction rate of liquiritin in glycyrrhiza;liquiritin content was determined by HPLC.Result: The optimum extracting conditions were as follows: 10 times of 70% alcohol,each 3 h with two times.Conclusion: This procedure was efficient;the extraction technology is reasonable and can provide scientific basis for industrialize process.
出处 《中国实验方剂学杂志》 CAS 北大核心 2011年第10期30-32,共3页 Chinese Journal of Experimental Traditional Medical Formulae
基金 吉林省科技发展计划项目(20080918)
关键词 正交试验 甘草 甘草苷 提取工艺 orthogonal test glycyrrhiza liquiritin extracting technology
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