多排CT评价左侧冠状动脉前降支狭窄对左心功能的影响

The Influence of Left Anterior Descending Coronary Artery Stenosis on Left Ventricular Function with Multidetector CT

目的利用多排CT对左侧冠状动脉前降支（LAD）狭窄程度及左心功能进行评价,并研究二者的相关性。方法回顾性分析196例于心脏科就诊并行冠状动脉CT造影（CTA）检查的患者,按左前降支狭窄程度不同将其分成正常组、A组（正常及狭窄〈25%）、B组（25%-49%）、C组（50%~74%）、D组（≥75%）共5组,准确测量每例患者的左心室舒张末期容积（EDV）、左心室收缩末期容积（ESV）、左心室射血分数（EF）等指标,并进行统计学分析。结果左心室射血分数（EF）分别为正常组（60.90±5.79）%、A组（60.27±5.53）%、B组（59.17±6.11）%、C组（61.25±6.02）%、D组（51.14±7.27）%,统计分析显示A、B、C各组与正常组数据间差异无统计学意义（P〉0.05）,D组和正常组组间ESV、SV、EF值差异均有统计学意义（P〈0.05）。结论多排CT能准确评价冠状动脉及左心功能,且左前降支狭窄对左心功能有一定影响。

Objective To evaluate the left anterior descending coronary artery stenosis,left ventricular function and correlation by using multidetector CT.Methods 196 patients with coronary atherosclerotic heart disease（CHD） were retrospectively analyzed.According to different degrees of left anterior descending artery stenosis,the patients were divided into five groups as normal,A（25%）,B（25% to 49%）,C（50% to 74%）,and D（≥75%）.Left ventricular end diastolic volume（EDV）,left ventricular end systolic volume（ESV）,left ventricular ejection fraction（EF） were accurately measured and statistically analyzed.Results In the normal,A,B,C,and D groups,the mean left ventricular EF were（60.90±5.79）%,（60.27±5.53） %,（59.17±6.11） %,（61.25±6.02） %,（51.14±7.27） %,respectively.There was no significant difference between A,B,C and normal groups.Compared with the normal groups,the D group showed difference in ESV,SV,EF values（P〈0.05）.Conclusion The influence of left anterior descending coronary artery stenosis on left ventricular function could be accurately evaluated by multidetector CT scan.