聚丙烯微孔膜荷负电表面的构建与阻抗蛋白质吸附性能

Construction of negatively charged surface on polypropylene microporous membrane and its resistance to protein adsorption

报道一种有效构建聚丙烯微孔膜(PPMM)荷负电表面的新方法。组合大气压介质阻挡放电等离子体预处理和界面交联技术,制得表面荷正电的PPMM;通过动态静电自组装技术将阴离子聚电解质固定到膜表面,从而获得荷负电的PPMM。ATR-FTIR、XPS和FESEM分析确证了修饰过程中膜表面化学组成与形貌的变化。静态水接触角和纯水通量实验结果显示,荷负电PPMM表面亲水性显著改善,水通量增大。当组装密度为53.0μg.cm-2时,水通量达(2445±95)L.(m2.h)-1,为未修饰PPMM的2.9倍。蛋白质溶液过滤实验表明,表面荷负电PPMM能有效阻抗带负电蛋白质的吸附。

To improve the antifouling ability of polypropylene microporous membrane（PPMM）,a facile surface modification approach was developed based on the assembly of negatively charged biomacromolecules.The PPMM surface was first endowed with a permanently positively charged coating layer by combining a pretreatment using dielectric barrier discharge plasma under atmospheric pressure with interfacial crosslinking.Then polyelectrolyte bearing negative charges was immobilized on the surface by dynamic electrostatic self-assembly.The surface chemical composition and morphology of the modified membranes were confirmed by ATR-FTIR,XPS,and FESEM.Static water contact angle and pure water flux measurements were also conducted.It was found that surface hydrophilicity of the negatively charged membrane was greatly enhanced and water flux increased remarkably.When assemble density reached 53.0 μg·cm-2,water flux was（2445±95） L·（m2·h）-1,which was 2.9 times as high as that of the unmodified membrane.Furthermore,protein solution filtration suggested strong resistance of these negatively charged membranes to the adsorption of negatively charged proteins.