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丙泊酚复合瑞芬太尼麻醉在乳腺小手术中的应用

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摘要 目的:探讨在乳腺小手术中应用丙泊酚复合瑞芬太尼麻醉的效果。方法:瑞芬太尼1.5ug/kg、丙泊酚2mg/kg缓慢静脉输注诱导,患者入睡后丙泊酚4mg/(kg·h)、瑞芬太尼1.0ug/(kg·min)持续静脉输注;术中根据患者体动、BP、HR等变化调整异丙酚用量,二组均在缝合皮肤时停药。观察患者血流动力学变化。结果:丙泊酚复合瑞芬太尼组在诱导麻醉后5min、切皮时的MBP、HR均低于麻醉前,差异有显著性意义,其余时间差异无统计学意义。丙泊酚复合氯胺酮组用药前后血流动力学变化无统计学意义。丙泊酚复合瑞芬太尼组苏醒时间为(4.6±1.8)min,无苏醒期躁动、精神障碍,恶心呕吐发生率10%,均低于丙泊酚复合氯胺酮组的(11.3±3.2)min、20%、10%和30%,差异有统计学意义(p=0.000)。结论:丙泊酚复合瑞芬太尼静脉输注麻醉适合在乳腺小手术应用,其安全性高,操作简单,易于控制药量。
作者 杨涛
出处 《医学信息(下旬刊)》 2011年第2期59-60,共2页 Medical information
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