粪链球菌与动脉粥样硬化关系的研究

THE INVESTIGATION OF THE RELATION BETWEEN STREPTOCOCCUS FECALIS AND ATHEROSCLEROSIS

从人体粪便中分离一株粪链球菌,并研究了它与动脉粥样硬化症之间的关系。实验结果表明,用粪链球菌免疫或口服粪链球菌可降低血清胆固醇或甘油三酯水平。粪链球菌免疫对HDL-ch有增加倾向,但无统计学意义;它可降低全血表观粘度和血浆表观粘度,但与对照组表观粘度比较则无差异。实验未发现粪链球菌免疫可减轻动脉粥样硬化病变。

The streptococcus recalls were isolated from human feces, to study it's relation with atherosclerosis has been completed in present paper. Experimental results indicate that immunization or oral administration with streptococcus reduce the levels of TC or TG. The immnunization with streptococcus shows a tendency to increase the levels of HDL-ch, but it does not reaches a statistical significance. The immunization with streptococcus can decrease in the viscosity of the whole blood and the plasma in itself comparison, but it's viscosity, to compare with control group have not significant. We observe that the immunization with streptococcus has not decreased in the atherosclerotic lesions in present experiment.