糖尿病合并痰菌阳性肺结核病80例临床分析

Clinical Analysis of 80 Cases with Diabetes Combined with Smear-positive Pulmonary Tuberculosis

目的评价糖尿病合并肺结核痰菌阳性患者的治疗效果。方法观察80例糖尿病合并肺结核痰菌阳性患者,用口服降糖药或胰岛素控制血糖,按2E3H3R3Z3/H3R3标化抗结核治疗,随诊1年并监测血糖、糖化血红蛋白及痰菌转变。结果 6个月疗程痰菌阴转率为98.7%,随诊1年痰菌阴性率为97.4%;X线胸片渗出病变大部分吸收,空洞大部分闭合;而血糖平均控制水平一般。结论糖尿病合并肺结核痰菌阳性中结核菌有一定的耐药率,易出现空洞,血糖的控制并不完全影响肺结核的控制。

Objective To evaluate the treatment effectiveness to patients with diabetes combined with smear-positive pulmonary tuberculosis.Methods 80 patients with diabetes combined with smear-positive pulmonary tuberculosis adopted oral blood glucose lowering drugs or trypsin to control blood sugar,anti-tuberculosis according to 2E3H3R3Z3/H3R3 standardization,and observe blood sugar,glycosylated hemoglobin and sputum conversation during one year follow-up.Results The negative conversion rate of phlegm bacteria after six months treatment course was 98.7%,the negative rate of phlegm bacteria was 97.4% after 1 year follow-up;main sternum exudation lesion assimilated,cavitary closed;the average control level of blood sugar was common.Conclusion Diabetes combined with smear-positive pulmonary tuberculosis had drug resistance,was easy to appear cavity,the control of blood sugar cannot fully influence Pulmonary tuberculosis.