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多酚姜黄素类似物的一步合成 被引量：2

One-step Synthesis of Polyphenolic Curcumin Analogues
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摘要 以无水乙醇或THF为溶剂,浓盐酸为催化剂,含羟基芳香醛可以在不保护酚羟基的情况下与酮一步完成缩合反应,合成了12个多酚姜黄素类似物,产率62%～98%,其结构经1H NMR,MS,IR和元素分析确证。 Without phenol protection,12 polyphenolic curcumin analogues in yields of 62%～98% were sysnthesized by one step condensation of appropriate ketone and aromatic aldehydes in the presence of concentrated hydrochloric acid in ethanol or THF.The structures were confirmed by 1H NMR,MS,IR and elemental analysis.
作者 杜志云 涂增清 张焜 莫容清 汤志恺
机构地区 广东工业大学轻工化工学院
出处 《合成化学》 CAS CSCD 北大核心 2011年第3期385-388,共4页 Chinese Journal of Synthetic Chemistry
基金 广东省科技计划资助项目(2007A020300007-10)
关键词 多酚姜黄素 羟基芳香醛 酚羟基保护 合成 polyphenolic curcumin analogues phenol protection aromatic aldehyde synthesis
分类号 O626.3 [理学—有机化学]
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参考文献11

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共引文献14

同被引文献26

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合成化学
2011年 第3期

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