摘要
目的优选瘀肿消温度敏感型原位凝胶的基质配比。方法以温度敏感型原位凝胶的胶凝温度、胶凝强度、生物黏附力为考察指标,优选出瘀肿消温度敏感型原位凝胶基质配比。结果瘀肿消温度敏感型原位凝胶基质配方Poloxamer407、Poloxamer188、卡波姆分别为22%、3%、0.7%。结论瘀肿消温度敏感型原位凝胶成型工艺简单、性质稳定。
Objective Optimization of Matrix matching for Stasis extinction Temperature-sen sitive situ gel.Method Gelation temperature,gel strength and bioadhesive force of Temperature-sensitive situ swelled gel is index,optimization of Matrix matching for Stasis extinction Temperature-sensitive situ gel.Results Poloxamer407,Poloxamer188,Carbopol of Matrix matching for Stasis extinction Temperature-sen sitive situ gel respective is 22%,3%,0.7%.Conclusion Molding process is simple,nature is stable of Stasis extinction Temperature-sen sitive situ gel.
出处
《中国医药指南》
2011年第14期5-5,11,共2页
Guide of China Medicine
基金
湖南省卫生厅基金项目(2008088)
关键词
温度敏感型原位凝胶
基质配比
Temperature-sensitive situ gel
Matrix matching
