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他汀类药物治疗颈动脉斑块疗效分析 被引量:6

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摘要 目的分析探讨他汀类药物(阿托伐他汀)治疗颈动脉斑块的临床治疗效果。方法收集河南永煤集团总医院2008年1月至2010年12月期间颈动脉斑块患者共64例,按照随机分为实验组和对照组,每组各32例,对照组给予常规治疗及饮食控制,实验组在对照组基础上给予予阿伐他汀,观察时间为6个月,治疗前后分别测量颈动脉IMT和斑块大小。结果实验组治疗后斑块面积、IMT与治疗前相比明显减少(P<0.05),实验组治疗前后的指标的差值较对照组有明显的提高,差异具有统计学意义(P<0.05);实验组中治疗后各血脂水平较对照组,明显下降,差异具有显著性(P<0.05)。结论阿托伐他汀可调整血脂水平,减缓或逆转颈动脉IMT及面积,稳定了颈动脉斑块,对颈动脉斑块有一定的治疗作用,值得临床应用推广。
作者 郑艳
出处 《中国医药指南》 2011年第14期241-242,共2页 Guide of China Medicine
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