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MKK4与恶性肿瘤相关性的研究进展 被引量：6

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摘要 随着生物学研究的不断深入,临床对受体型酪氨酸激酶（PTK）及其相关信号通路在肿瘤生长、侵袭、血管生成中的作用有了更加深入的了解。丝裂原活化蛋白激酶（MAPKs）作为信号传导通路的重要组成部分,是细胞内的一类丝氨酸／苏氨酸蛋白激酶，其信号转导通路存在于大多数细胞内，
作者 鲁明骞 许新华
机构地区 宜昌市中心人民医院三峡大学第一临床医学院 三峡大学肿瘤研究所
出处 《山东医药》 CAS 北大核心 2011年第19期110-111,共2页 Shandong Medical Journal
关键词 丝裂原活化蛋白激酶激酶4 恶性肿瘤 信号传导
分类号 R730.53 [医药卫生—肿瘤]
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参考文献13

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同被引文献86

  • 1董宏丹.苦参碱对荷4T1小鼠乳腺癌肿瘤模型JNK1/AP-1信号通路的影响[J].辽宁中医药大学学报,2019,0(11):64-68. 被引量：8
  • 2闫恩志,金英,范莹,杨菁,宗志红,齐志敏.阿魏酸钠对淀粉样β蛋白片段1～40引起的大鼠海马MAP激酶信号传导通路及凋亡蛋白表达的影响[J].中国药理学与毒理学杂志,2007,21(5):385-392. 被引量：9
  • 3Chen L, H u CS, Chen XZ, et al. Concurrent chemoi-adiother-rapy plus adjuvant chemotherapy versus cencurrent chemo-therapy alone in patients with locoregionally advanced naso-pharyngeal carcinoma: a pi us 3 multi centre randornised con-trolled trial[J]. Lancet Oncol,2012,13(2) :163-171.
  • 4Zhou Xv CuiJ,Macias Vv et al. The progress on genetic analysis of nasopharyngeal caicinomay[J]. Comp Funct Ge-nomics,2007 :57513.
  • 5Dong x.u Y,Du Mvet al. P38 mitogen-activated protein kinase inhibition attenuates pulmonary inflammatory response in a rat cardiopulmonary bypass model[J]. EurJ Cardiothorac Surg, 2006,30(1) : 77-84.
  • 6Cheng YJ, Lee CH, Lin YP, et al. Caspase-3 enhances lung metastasis and cell migration in a protease-independent mechanism through the ERK pathway[J]. IntJ Canc-er,2008,123(6):1278-1285.
  • 7Spillman MA,LacyJ ,Murphy SK,et al. Regulation of the metastasis suppressor gene MKK4 in ovarian cancerJ J], Gynecol Oncol,2007 ,105(2) :312-320.
  • 8Sousa H, Pando M, Breda E, et al. Role of the MDM2 SNP309 polymorphism in the initiation and early age of onset of nasopharyngeal carcinoma[J]. Mol Carcinog, 2011,50(2) :73-79.
  • 9XU YF, Liu WL, DongJQ, et al. Sequencing of DC-SIGN promoter indicates an association between promoter variation and risk of nasopharyngeal carcinoma in cantonese[J]. BMC Med Genet,2010,l1:161.
  • 10Farhat K, Hassen E, Bouzgarrou N, et al. Functional IL- 18 promoter gene polymorphisms in Tunisian nasopharyngeal carcinoma patients[J]. Cytokine , 2008,43 (2): 132-137.

引证文献6

二级引证文献24

山东医药
2011年 第19期

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