埃索美拉唑与奥美拉唑在胃溃疡治疗中的效果比较

The effects comparison of Esomeprazole and Omeprazole in the treatment of gastric ulcer

目的:比较埃索美拉唑与奥美拉唑在胃溃疡治疗中的效果。方法:将我院收治的95例胃溃疡患者随机分为两组,对照组45例患者采用奥美拉唑、阿莫西林、克拉霉素治疗,观察组45例患者采用埃索美拉唑、阿莫西林、克林霉素治疗,观察比较两组的临床效果。结果:观察组总有效率为98.0%,明显高于对照组的82.2%,两组间有显著性差异(P<0.05),两组均无明显不良反应发生。结论:埃索美拉唑应用于胃溃疡的治疗中疗效更为满意,且无明显不良反应,值得临床关注。

Objective： To compare the clinical effect of Esomeprazole and Omeprazole in the treatment of gastric ulcer. Methods： 95 patients of gastric ulcer were randomly divided into two groups, the control group （45 cases） were treated by Omeprazole, Amoxicillin and Clindamycin, the observation group （50 cases） were treated by Esomeprazole, Amoxicillin and Clindamycin, the efficacy of the two groups were observed and compared. Results： The total effective rate in observation group was 98.0%, significantly higher than 82.2% of control group, there was a sig- nificant difference between two groups （P〈0.05）. There were no obvious adverse reactions in two groups. Conclusion： Esomeprazole in the treatment of gastric ulcers are more satisfied and no obvious side effects, is worthy of attention.