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法莫替丁与奥美拉唑治疗反流性食管炎临床对比研究 被引量:2

The clinical comparative effect of famotidine and omeprazole used for patients with reflux esophagitis
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摘要 目的:比较法莫替丁与奥美拉唑治疗反流性食管炎的临床效果,探讨更为合适的治疗药物.方法:100例反流性食管炎患者作为研究对象,被随机分为实验组和对照组,对照组给予法莫替丁治疗,实验组给予奥美拉唑治疗.结果:实验组痊愈率(X2=4.290,P〈0.05)和总有效率(X2=4.761,P〈0.05)均显著优于对照组,显示了更好的临床效果.结论:奥美拉唑应用于反流性食管炎患者,能保证安全性,改善临床效果,显著提高患者生活质量,值得临床考虑应用. Objective: To compare the clinical effects of famotidine and omeprazole used for patients with reflux esophagitis, and choose the more proper drugs for patients. Methodsil00 cases of patients as studied object were randomly divided into experimental group and control group, control group was given therapy of famotidine, and experimental group was given therapy of omeprazole. Results: The cured rate(X^2=4. 290,P〈0.05) and total effective rate (X^2 =4. 761 ,P〈0.05)in experimental group was significantly better than that in control group, and showed better clinical effect. Conclusions : Omeprazole used for patients with reflux esophagitis can guarantee the safety, reach up to better clinical effect and improve the life quality of patients, sO it deserved applying in clinical work.
作者 戴英林
出处 《医学信息(下旬刊)》 2011年第4期61-61,共1页 Medical information
关键词 法莫替丁 奥美拉唑 反流性食管炎 Famotidine Omeprazole Reflux esophagitis
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  • 1]许国铭.胃食管反流病研究进展[M].第五届全国胃病学术大会汇编,2002,100.
  • 2HaukeelandJG.胃酸—埃索美拉唑和其他质子泵抑制剂的比较.消化电子快讯,2003,1:9-9.
  • 3李瑜元.酸相关性疾病治疗的抑酸水平及药物选择[M].第五届全国胃病学术大会汇编,2002,61.
  • 4DE Vault KR, Castell DO. The paramenters committee of the American college of gastroenterology. Updated guidelines for the diagnosis and treatmeng of gastroesophageal reflux disease. Am J Gastroenterol, 11999, 94:1434.
  • 5Peghini PL, Katz PO, Castell DO. Ranitidine controls nocturnal gastric acid breakthrough on omeprazole~ a controlled study in normal subjects. Gastroenterology, 1998,115:1335.
  • 6Hatlebakk JG, Katz PO, Camacho -- Lobato L, et al. Proton punp inhibitors:better acid suppression when taken befor a meal than without a meal. Aliment Pharmacol Ther,2000, 14:1267.
  • 7Nzeako UC, Murray JA. An evaluation of the clinica: implications of acid breakthrong in patients on proton pump inhibitor therapy. Aliment Pharmacol Ther,2002,16: 1309.
  • 8Fackler WK, Ours TM, Vaezi MF,et al. Longterm effect of H2RA therapy on nocturnal gastric acid breakthrough. Gastroenterology, 2002,122 : 625.
  • 9Xue S, Kate PO, Banerjee P, et al. Bedtime H2 blockers improve nocturnal gastric acid control in GERD patients on proton pump inhibitions. Aliment Pharmacol Ther,2001,15:1351.
  • 10许国铭,邹多武.兰索拉唑治疗反流性食管炎多中心临床观察[J].中华消化杂志,1999,19(4):243-245. 被引量:77

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