桥本脑病的MRI表现(附1例报告及文献复习)

MR Findings of Hashimoto's Encephalopathy:a Case Report and Literature Review

目的探讨桥本脑病的磁共振表现和文献复习。方法回顾性分析1例临床确诊的桥本脑病资料,并复习国内外相关文献。结果本例桥本脑病MRI表现为脑内弥漫分布长T1、长T2信号病灶,Flair上病灶呈高信号,双侧大脑及小脑半球病灶分布基本对称,增强扫描显示无强化。弥散加权成像上,病灶呈高信号,ADC图上呈等或稍高信号。结论桥本脑病MRI表现缺乏特异性,其主要累及脑白质,病灶可在一段时间内消失,该病最终的确诊需要结合实验室检查及临床特点。

Objective To investigate MRI manifestations of Hashimoto＇s encephalopathy,and review recent literatures related to Hashimoto＇s encephalopathy at home and abroad.Methods To analyze a case of HE confirmed by clinic retrospectively according to literatures at home and abroad.Results MRI of the brain in this case showed a mild nonspecific pattern of diffusely increased signal intensity within the bilateral cerebrum and cerebellum white matter on T2 and FLAIR images without any enhancement.Diffusion-weighted MRI（DWI） reveals hyperintensity with slightly increased apparent diffusion coefficient（ADC） values.Conclusion MR findings of Hashimoto＇s encephalopathy are lack of specificity,and they always show lesions in white matter which may disappear over a period of time.The diagnosis of HE needs combination with laboratory examination and clinical presentations.