摘要
目的:探讨肝上皮样血管平滑肌脂肪瘤的病理诊断及鉴别诊断.方法:收集武钢总医院病理科2007-2009年手术切除肝上皮样血管平滑肌脂肪瘤标本2例,对2例肝上皮样血管平滑肌脂肪瘤相关临床资料、病理学特征及免疫组织化学进行观察分析并复习相关文献.结果:2病例均为女性,巨检境界较清楚,镜下见肿瘤主要由弥漫的上皮样细胞构成,排列呈不规则梁索状结构,瘤细胞圆形或多角形,核呈圆形或卵圆形,无明显异型性.免疫组织化学示HMB45、Melan-A和SMA均有阳性表达.结论:肝上皮样血管平滑肌脂肪瘤是极为罕见的间叶性肿瘤,其诊断及鉴别诊断主要依靠组织病理学及免疫组织化学.
AIM:To investigate the clinicopathologic characteristics of hepatic epithelioid angiomyolipoma (EAML).METHODS:Two cases of hepatic EAML treated at General Hospital of Wuhan Iron and Steel Corporation from 2007 to 2009 were analyzed in this study.The clinicopathologic and immunohistochemical characteristics of the disease were described and the related literature was reviewed.RESULTS:Both patients are female.Both cases of hepatic EAML had clear boundaries.The tumors were characterized by diffused epithelioid neoplastic cells.The epithelioid cells were round with eosinophilic or clear cytoplasm,and few neoplastic cells showed cellular atypia.Immunohistochemically,the neoplastic cells were diffusely positive for HMB45,Melan-A and SMA.CONCLUSION:Hepatic EAML is a rare mesen-chymal neoplasm.The diagnosis and differentiatial diagnosis of EAML rely mainly on histopathology and immunohistochemistry.
出处
《世界华人消化杂志》
CAS
北大核心
2011年第10期1071-1074,共4页
World Chinese Journal of Digestology