急性脑梗死合并糖代谢异常患者发病初期中医证候分析

Analysis on the TCM syndromes of the Early Stage of Acute Cerebral Infarction Complicated with Glycometabolic Abnormality

目的研究急性脑梗死合并糖代谢异常患者在脑梗死发病初期中医证候的分布特点。方法对224例急性脑梗死患者进行血糖检测,并采用美国国立卫生研究院卒中量表(NIHSS)进行神经功能缺损评分,同时对患者的中医证候进行评分,分析急性脑梗死合并糖代谢异常者的证候特点。结果急性脑梗死合并糖代谢异常患者121例,无糖代谢异常者103例;急性脑梗死合并糖代谢异常患者的NIHSS评分高于无糖代谢异常患者(P<0.05),急性脑梗死合并糖代谢异常组患者的高血压患病比例明显高于无糖代谢异常组的患者(P<0.01),急性脑梗死合并糖代谢异常组火热证例数比例较无糖代谢异常患者要高(P<0.05),两组分布前10位的中医证候类型大体相似。结论急性脑梗死合并糖代谢异常患者火热证多于无糖代谢异常患者,神经功能缺损也较严重,且多合并高血压病。

Objective To study the distribution characteristics of TCM syndromes of acute cerebral infarction（ACI） patients accompanied with glycometabolic abnormality in the early stage.Methods Totally 224 ACI paients were given blood glucose test and were scored with National Institute of Health Stroke Scale（NIHSS） for evaluating neural function defect.Meanwhile their TCM syndromes were scored for analyzing the syndrome characteristics of ACI accompanied with glycometabolic abnormality.Results There were 121 patients of ACI accompanied with glycometabolic abnormality and 103 cases without glycometabolic abnormality.The NIHSS score of ACI patients accompanied with glycometabolic abnormality was higher than that without glycometabolic abnormality（P0.05）.The morbidity of hypertension of ACI patients with glycometabolic abnormality was significantly higher than that without glycometabolic abnormality（P0.01）.The cases of fire-heat syndrome in the ACI patients with glycometabolic abnormality were more than those in the ACI patients without glycometabolic abnormality（P0.05）.The first 10 TCM syndromes of the two groups were almost the same.Conclusion ACI patients with glycometabolic abnormality are more susceptible to fire-heat syndrome than those without glycometabolic abnormality,their neural function defect is more severe,and most of them are complicated with hypertension.