参七散对2型糖尿病患者血游离脂肪酸的影响

Influence of Shenqi Powder on Free Fatty Acid in the Blood of Type 2 Diabetes Mellitus Patients

目的观察参七散对2型糖尿病(T2DM)患者血游离脂肪酸(FFA)的影响。方法将169例T2DM患者随机分为治疗组89例,对照组80例。治疗组给予口服参七散5g/次,每日3次;对照组给予非诺贝特胶囊200mg/次,每日1次。两组均给药8周为1个疗程。治疗前后测定患者糖化血红蛋白(HbA1c)、空腹血糖(FBG)、餐后2小时血糖(2hPG)、甘油三酯(TG)、FFA的含量,同时记录体重指数(BMI)。结果治疗组治疗后HbA1c、FBG、2hPG及BMI与治疗前比较,差异均有统计学意义(P<0.05或P<0.01);两组患者治疗后血清FFA及TG水平与治疗前比较,差异均有统计学意义(P<0.05),但治疗后两组患者血清FFA及TG水平差异无统计学意义(P>0.05)。结论参七散能有效降低糖尿病患者的TG、FFA及血糖水平。

Objective To observe the influence of Shenqi Powder（Powder of American Ginseng and Noteginseng） on the free fatty acid（FFA） in the blood of type 2 diabetes mellitus（T2DM） patients.Methods Totally 169 T2DM patients were randomized into treatment group（89 cases）,and control group（80 cases）.The treatment group was administered Shenqi Powder for oral taking 5g each time,3 times per day.The control group was medicated with Fenofibrate Capsule 200mg each time,once per day.Both groups were treated for 8 weeks as one course.Before and after treatment,the contents of glycosylated hemoglobin（HbA1c）,fasting blood glucose（FBG）,2-hour blood glucose（2hBG）,triglyceride（TG）,and FFA were determined.At the same time,the body mass index（BMI） was recorded.Results After treatment,the contents of HbA1c,FBG,2hBG and BMI of the treatment group were statistically different from those before treatment（P0.05 or P0.01）.The contents of FFA and TG of both groups were statistically different from those before treatment（P0.05）.While the contents of FFA and TG of both groups were not statistically different after treatment（P0.05）.Conclusion Shenqi Powder is effective in decreasing the contents of TG,FFA,and blood glucose of T2DM patients.