期别不同对尘肺患者无通气期安全时限的影响

Effects of Different Pneumoconiosis Stages on Safe Duration of Apnea

目的探讨尘肺期别发展对患者氧储备能力的影响。方法 98例拟行全麻下大容量肺灌洗的成年男性尘肺患者按期别分为3组:Ⅰ组(Ⅰ期尘肺)34例,Ⅱ组(Ⅱ期尘肺)33例,Ⅲ组(Ⅲ期尘肺)31例。全部患者自主呼吸预氧合后全麻快诱导下行无通气期安全时限测定。比较各期患者由自主呼吸消失至脉搏氧饱和度(SpO2)降至95%,92%的时间。结果自主呼吸消失至SpO2降至95%、92%的时间Ⅲ组均明显较短(P<0.05),Ⅰ组、Ⅱ组间比较,差异无统计学意义(P>0.05)。结论尘肺患者随期别发展,其无通气期安全时限不断缩短,氧储备能力渐趋下降,晋级Ⅲ期者尤甚。

Objective To explore the effects of different pneumoconiosis stages on oxygen reserve.Methods 98 male pneumoconiosis patients scheduled for whole lung lavage were divided into group 1（stage Ⅰ,n=34）,group 2（stage Ⅱ,n=33）and group 3（stage Ⅲ,n=31）.All patients were pre-oxygenated using spontaneous tidal volume breathing via face mask for 5 min.Following induction of anesthesia,no ventilation occurred until oxygen saturation levels reached 92%.The times in every group were recorded when SpO2 reached 95% and 92% from the disappearance of spontaneous breath respectively.Results The times taken to reach SpO2 of 95% and 92% were significantly shorter in group 3 compared with group 2 and group 1.The times for SpO2 to reach 95% and 92% from disappearance of spontaneous breath in group 2 were longer than that in group 1,but there was no significant difference between two groups.Conclusions The safe durations of apnea and oxygen reserve gradually reduce along with pneumoconiosis stage development,patients in stage 3 were especially so.