摘要
白桦脂酸是一种五环三萜酸,存在于多种天然植物,特别是白桦树皮中,毒性低,安全指数高。近年来发现白桦脂酸具有抗肿瘤、抗HIV、抗炎、抗菌、抗疟疾等多种生物活性,特别是在抗黑色素瘤与抗HIV方面具有突出的表现,从而引起了人们极大的研究兴趣。对白桦脂酸的来源和生物活性进行了简要综述。
The betulinic acid（BA）,a type of pentacyclic triterpene acid,which is found in the bark of several species of plants,principally the white birch.It has a variety of biological activities,such as anti-tumor,anti-HIV,anti-inflammatory,antimicrobial,and antimalarial activity,especially in anti-melanoma and anti-HIV show great promise.In this paper,the preparation and bioactivities of betulinic acid are reviewed.
出处
《生命科学》
CSCD
北大核心
2011年第5期503-510,共8页
Chinese Bulletin of Life Sciences
基金
国家自然科学基金项目(20802020)
关键词
白桦脂酸
白桦脂酸制备
生物活性
肿瘤
抗HIV
betulinic acid
preparation of betulinic acid
biological activity
tumor
anti-HIV
