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福辛普利与比索洛尔联合治疗舒张性心力衰竭的疗效观察 被引量:7

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摘要 目的探讨福辛普利联合比索洛尔治疗左室舒张性心力衰竭的疗效。方法将92例左室舒张性心力衰竭患者单盲随机分为治疗组与对照组,对照组46例采用福辛普利片、利尿剂、硝酸酯类、醛固酮抑制剂抗心衰治疗,治疗组46例在以上治疗基础上加用比索洛尔,疗程6个月。比较2组临床疗效、心脏彩超左室舒张功能、血浆氨基末端B型钠利尿肽前体(NT-proBNP)等指标。结果治疗组总有效率98%,明显优于对照组的82%(P<0.05),在改善左室舒张功能指标方面治疗组也明显优于对照组(P<0.05),治疗组治疗后NT-proBNP(230.61±98.37)μg/L,与治疗前的(441.02±57.96)μg/L,及对照组治疗前后的(450.12±70.28)μg/L、(290.55±95.38)μg/L比较,均有显著性差异(P均<0.05)。结论福辛普利、比索洛尔联用治疗舒张性心力衰竭患者能有效缓解症状。
作者 马丹
出处 《现代中西医结合杂志》 CAS 2011年第17期2140-2141,共2页 Modern Journal of Integrated Traditional Chinese and Western Medicine
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参考文献5

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