SiO_2粉尘对巨噬细胞膜Mg^(2+)-ATP酶活性影响的时相研究——电镜酶细胞化学观察

Temporal Study on tne Effect of Silica on Mg^(2+)-ATPase Activity of the Membrane of Macrophages

本研究结果表明,SiO_2粉尘早期对细胞膜的损伤及其引起的膜通透性的改变可能是造成巨噬细胞不可逆损伤乃至死亡的主要原因。

An observation was made to investigate the relationship between the effect of silica on membrane Mg2+-ATPase activity of alveolar macrophages and silica-induced morphological alteration. The results showed that membrane damage by silica at early stage may be an main important reason for developing irrevesible cell injury and even cell death.