脑脊液置换术治疗蛛网膜下腔出血临床研究

Cerebrospinal Fluid Replacement Therapy for the Clinical Effects of Subarachnoid Hemorrhage

目的探讨脑脊液置换术治疗蛛网膜下腔出血的临床效果。方法将80例蛛网膜下腔出血患者随机分治疗组及对照组,各40例,治疗组在常规治疗的基础上进行脑脊液置换术治疗,对照组使用单纯的常规治疗。结果治疗组治疗的有效例数与对照组比较差异有统计学意义。治疗组中有头痛颈强者21例,持续时间6～12.5d,对照组头痛颈强持续时间14～21d,两组比较差异有统计学意义。治疗组中表现不同意识障碍者6例,经置换2～3次最短在4d内意识恢复正常,对照组意识障碍11例,意识障碍恢复时间6～14d,两组比较有显著差异。蛛网膜下腔出血3大并发症脑血管痉挛、脑积水、脑梗死,治疗组与对照组比较,均有显著差异。结论脑脊液置换术治疗蛛网膜下腔出血,能减少脑血管痉挛、脑积水、脑梗死等并发症,有利于患者恢复,操作简单易行、安全,疗效显著,值得临床推广应用。

Objective To investigate the cerebrospinal fluid replacement therapy for the clinical effects of subarachnoid hemorrhage.Methods 80 patients with subarachnoid hemorrhage were randomly divided into treatment group and 40 patients in the control group,treatment group,on the basis of conventional treatment of cerebrospinal fluid replacement therapy in the control group with conventional therapy alone.Results The number of cases of effective treatment and control groups significantly different.The treatment group had 21 cases of headache and neck strong,the shortest duration of 6d,the longest lasting 12.5d,the control group the duration of headache and neck strong shortest 14d,the longest 21d,two groups were significantly different.The performance of the different treatment groups in 6 cases of disturbance of consciousness,the replacement of 2 to 3 times the minimum in the 4d sense within the normal control group,11 cases of disturbance of consciousness,the shortest recovery of consciousness 6d,up to 14d,a significant difference between the two groups.In cerebral vasospasm,hydrocephalus,cerebral infarction which three complications subarachnoid hemorrhage,the treatment group and control group,there were significant differences.Conclusion Cerebrospinal fluid replacement in the treatment of subarachnoid hemorrhage,can reduce cerebral vasospasm,hydrocephalus,cerebral infarction and other complications,is conducive to patient recovery,simple operation,safety,efficacy and worth of clinical application.