运动对兔膝退变关节软骨形态学的影响

The Influence of Movement on the Morphology of the Degenerative Joint Cartilage of Rabbits

目的：了解不同运动方式对退变关节软骨的形态学影响。方法：以新西兰白兔为研究对象，用伸膝位石膏固定８周的方法建立ＯＡ动物模型，按运动方式不同，随机分成５组，从光镜、扫描电镜两方面观察运动对退变关节软骨的组织形态学影响。结果：关节制动可诱发关节软骨退变，运动对退变软骨具有保护和促进修复作用。结论：关节适宜运动可促进退变关节软骨的修复和重塑，增加关节稳定性。

Objective:To investigate the influence of different ways of movement upon the morphology of degenerative joint cartilage of rabbits.Method:Taking Newzealand rabbits as our study objects,we have built some OA animal models by fixing the rabbits left posterior knee joint in stretching state plaster caste for 8 weeks.According to different ways of movement,we observe the influence of movement upon the morphology of degenerative arthrochondritis under light microscopy and scanning electron microscopy.Result:Joint immobilization can evoke arthrochondritis degeneration,while movement can serve to protect and repair degenerative arthrochondritis.Conclusion:Joint movement of proper degree can help to repair and rebuild degenerative arthrochondritis,and make it more stable.