期刊文献+

吲哚胺2,3-二氧化酶对HepG2细胞生物学行为影响的研究 被引量:1

Effect of indoleamine 2,3-dioxygenase on the biological behaviour of HepG2 cells
原文传递
导出
摘要 吲哚胺2,3-二氧化酶(indoleamine 2,3-dioxygenase,IDO)是细胞内一种含亚铁血红素的酶,是肝脏以外惟一可催化色氨酸分子中吲哚环氧化裂解,从而沿犬尿酸途径进行分解代谢的限速酶,可将色氨酸分解为L-犬尿酸、吡啶甲酸和喹啉酸等多种代谢物.
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2011年第5期380-381,共2页 Chinese Journal of Hepatology
基金 山西省科研攻关项目(200903110)
关键词 吲哚胺-吡咯2 3-二氧化酶 肿瘤浸润 细胞黏附 Indoleamine-pyrrole 2,3-dioxygenase Neoplasm invasiveness Cell adhesion
  • 相关文献

参考文献6

  • 1Muller AJ,Prendergast GC.Indoleamine 2,3-dioxygenase in immune suppression and cancer.Curr Cancer Drug Targets,2007,7:31-40.
  • 2Inaba T,Ino K,Kajiyama H,et al.Indoleamine 2,3-dioxygenase expression predicts impaired survival of invasive cervical cancer patients treated with radical hysterectomy.Gynecol Oncol,2010,117:423-428.
  • 3Pan K,Wang H,Chen MS,et al.Expression and prognosis role of indoleamine 2,3-dioxygenase in hepatocellular carcinoma.J Cancer Res Clin Oncol,2008,134:1247-1253.
  • 4Wicki A,Lehembre F,Wick N,et al.Tumor invasion in the absence of epithelial-mesenchymal transition:podoplanin-mediated remodeling of the actin cytoskeleton.Cancer Cell,2006,9:261-272.
  • 5Barth MC,Ahluwalia N,Anderson TJ,et al.Kynurenic acid triggers firm arrest of leukocytes to vascular endothelium under flow conditions.J Biol Chem,2009,284:19189-19195.
  • 6Blanc JF.Bisson C,Frankenne F,et al.Hepatocarcinoma cell lines down-regulate matrix metalloproteinase-2 expression in human hepatic myofibroblasts.Int J Oncol,2002,20:1129-1136.

同被引文献3

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部