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经直肠能量多普勒显像评价高强度聚焦超声治疗前列腺增生的微血管变化 被引量:2

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摘要 目的探讨经直肠能量多普勒显像(PD I)显示高强度聚焦超声(HIFU)治疗良性前列腺增生(Ben ign prostatic hyperplasia,BPH)的微血管变化情况,用以评估HIFU治疗的有效性。方法对20例经HIFU治疗后的BPH患者进行12个月的观察随访,采用国际前列腺症状评分(IP-SS)、生活质量评估(QOL)、最大尿流率(Qm ax)、前列腺体积(Vp)和残余尿量(RUV)进行临床疗效评估,应用经直肠PD I观察前列腺的微血管变化,利用Photoshop软件测量前列腺组织内彩色面积像素值占前列腺总面积像素值的百分比(BCR),与各临床疗效指标进行相关性分析。结果术后IPSS评分和QOL评分降低,RUV减少,Qm ax提高,Vp明显缩小(P<0.01),随访至术后12个月时PD I测定的BCR值均<5%,且与各临床指标有较好的相关性(P<0.05)。结论经直肠PD I具有灵敏、准确、便捷等优点,BCR可以方便、有效地显示前列腺的形态及微血管变化,能够对于HIFU治疗BPH的疗效进行客观的评价,并指导进一步治疗。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2011年第9期1518-1519,共2页 Chinese Journal of Gerontology
基金 上海市嘉定区科委科研项目〔(2006)JKK027〕
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参考文献8

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