摘要
目的探讨苏州地区儿童急性呼吸道副流感病毒3型(Pinf-3)感染流行与气候因素的相关性。方法连续四年对因呼吸道感染而住院的6655例儿童进行病毒病原学监测。运用直接免疫荧光法检测呼吸道分泌物中Pinf-3抗原。同时收集2006~2009年苏州地区月平均气温、月平均湿度、月总雨量、月总日照、月平均风速等有关气象资料。采用直线回归和逐步回归法研究病毒活性与气候因素的相关性。结果Pinf-3检出率为2.75%,4年阳性率分别为2.31%、2.50%、3.32%和2.92%,年度间阳性率无统计学差异(P〉O.05)。从季节分布来看,Pinb3好发于春夏季,夏季明显高于冬季(4.50%VS.1.30%)(P〈O.01)。Pinf-3阳性率与月平均气温呈正相关(P〈0.01)。结论Pinf-3流行活性与气候相关,尤其是气温对Pinf-3的流行活性影响最大。
Objective To study the relationship of meteorological conditions and epidemic activity of parainfluenza viruse-3. Methods Samples of 6655 children hospitalized with acute respiratory tract infections (ARIs) during year 2006 to 2009 were tested for parainfluenza viruse-3 with direct immunofluorescence assay. Meteorological conditions including mean temperature, relative humidity, rainfall amount, sum of sunshine and mean wind velocity were collected monthly. The relationship between the activity of parainfluenza viruse-3 and metrorological conditions was analyzed by linear regression and stepwise regression analysis. Results Parainfluenza viruse-3 was identified in 2.75% of 6655 specimens. There was no significant difference in positive rate among 4 years (P〈0.05). The positive rate was 4. 5% in summer, whichwas higher than 1.30% in winter (P〈0. 01). The activity of parainfluenza viruse-3 was positively correlated with mean temperature. Conclusion The epidemic activity of parainfluenza viruse-3 is related to the meteorological conditions, especially mean temoerature.
出处
《江苏医药》
CAS
CSCD
北大核心
2011年第8期932-934,共3页
Jiangsu Medical Journal
关键词
副流感病毒3型
急性呼吸道感染
气候因素
儿童
Parainfluenza viruse-3
Acute respiratory tract infectiom Meteorological conditions
Children