硒易感性疾病病区自然演变对硒营养依存性的研究

A Study on Dependence of Natural Regression of Selenium Responsive Diseases Areas Upon Selenium Nutrition Level

对我国典型大骨节病病区病情和硒营养的关系进行了三年现场监测和调查，结果表明：病情依硒营养水平而变化。随着农村改革开放的深入发展，经济状况有了显著改善，病区居民膳食结构发生了明显改变，外源性高硒食物输入增加，膳食中高硒食物比例不断提高，使食物链的物质循环由自给自足的封闭状态向半开放—开放的模式转化，人体硒营养水平相应提高，从而逐渐降低了对原生低硒环境的依赖性，病区因此自然演变为轻或非病区。

Authors had studied the relationship between patient's condition and selenium nutrition status in typical Kaschin Beck disease areas through on the spot experiments for three years, and results of the tests indicated that change of patient's condition depended on selenium nutrition level. Residential food compositions of disease areas had changed obviously with striking improvenent of economic situation and the adoption of reform and opening to the outside world policies in rural regions. Because of increasing of exogenous selenium input, the proportion of high selenium food in meals in disease areas was raised constantly, which changed material cycle of food chain from a closed self sufficiency situation to a semi opening or an opening model, then residential selenium nutrition level was raised relevantly and was reduced the regressed into minor diseases or non diseases areas naturally.