金边瑞香化学成分

Chemical constituents of Daphne odora var.margirmta

目的:对金边瑞香的化学成分进行研究。方法:采用硅胶,ODS,Sephadex LH-20柱色谱等方法对金边瑞香70%乙醇提取所得褐色固体析出物进行化学成分研究,并采用UV,1H-NMR,13C-NMR,MS,CD等光谱技术鉴定其结构。结果:从金边瑞香中分离得到10个化合物,经鉴定为荛花醇B(1)、山奈酚(2)、瑞香黄烷B(3)、瑞香黄烷D2(4)、瑞香黄烷A(5)、瑞香黄烷C(6)、瑞香黄烷D1(7)、瑞香黄烷I(8)、瑞香素(9),双白瑞香素(10)。结论:化合物1,2,4为首次从金边瑞香中分离得到,其中化合物1为首次从该属植物中得到。

Objective： To study the chemical constituents of Daphne odora var.margirmta.Method： The compounds were isolated and purified by column chromatography of silica gel,ODS,Sephadex LH-20,and their structures were identified by UV,1H-NMR,13C-NMR,MS and CD spectroscopic methods.Result： Ten compounds were elucidated as wikatrols B（1）,kaempferol（2）,daphnodorin B（3）,daphnodorin D2（4）,daphnodorin A（5）,daphnodorin C（6）,daphnodorin D1（7）,daphnodorin I（8）,daphnetin（9）,daphnoretin（10）.Conclusion： Compounds 1,2,4 were obtained from this plant for the first time,and compound 1 was isolated firstly from the genus Daphne.