近视眼人群角膜Q值与像差的相关性分析

Correlation analysis of corneal Q-value and aberration in myopia population

目的研究近视人群眼角膜非球面特性（Q值）与高阶像差的相关性。方法随机收集近视屈光手术患者300例（600眼）,使用0 rbscan IIz眼前节分析系统K＆Q计算软件获得600眼角膜6mm分析区域的Q值,Zywave波前像差仪测量瞳孔直径6mm眼内总体像差、高阶像差和球差的均方根值（RMS）值,并针对Q值的分布特征及像差进行相关分析。结果 300例600眼角膜Q值分布范围-0.51-0.37,平均-0.17±0.11,6mm瞳孔直径的总像差均方根值平均为（9.25±2.63）μm,高阶像差均方根值平均为（0.43±0.16）μm,球差均方根值平均为（0.06±0.05）μm。Q值与球差均方根值呈正相关,但与总像差均方根值和高阶像差均方根值均不相关。结论近视眼人群角膜Q值呈近似正态分布,角膜Q值与球差存在相关性。

Objective To study myopia population of corneas aspherical characteristics（Q value） and high-order correlation.Methods Six hundred eyes of 300 patients with myopia for corneal laser refractive surgery were enrolled in this study with each patient selected randomly.The K＆Q calculator of 0rbscan IIz anterior segment system was used to obtain the Q-value of 6mm optical zone in 300 cases（600 eyes）,and statistical analysis was used to comprehend the distribution characters of Q-value,Zywave wave front instrument measuring intraocular overall aberration,high-order correlation and spherical correlation of the RMS value under the 6mm pupil diameter,and statistical analysis was used to comprehend the distribution characters of Q-value and correlation.Results The Q-value of 600 eyes ranged from-0.51～0.37 with the mean value（-0.17±0.11）,6mm pupil diameter of the total aberration of the RMS value with the mean value（9.25±2.63）μm,high-order correlation of the RMS value with the mean value（0.43±0.16）μm,spherical correlation of the RMS value with the mean value（0.06±0.05）μm.The Q-value showed a positive correlation with spherical correlation,but no relation with overall aberration of the RMS value and high-order correlation of the RMS value.Conclusion The Q-value of 600 eyes of（300 cases） were approximately normal distribution.The Q value was related with spherical correlation.